Wingman follows the adventures of two best friends, Hank and Max, whose main mission in life is picking up women. Hank, more confident and good looking than Max, is the stud of the two while Max is mostly relegated to wingman status. One day, lightning (literally) strikes and alters Hank's chemistry such that he's no longer able to pick up women. However, women now find any man within a few feet of Hank irresistible thus Max instantly goes from Wingman to Cassanova. Hank and Max both struggle in handling this role reversal on their way to finding true love.